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Erythromelalgia (EM) is a rare neurovascular pain disorder that can cause redness and pain in all parts of the body, but most frequently the extremities, such as the hands and feet. It is characterized by intense burning pain, severe redness (erythema), and increased skin temperature that may be episodic or almost continuous in nature. The specific underlying cause of EM remains unknown.
Erythromelalgia may occur either as a primary or secondary disorder (i.e. a disorder in and of itself or a symptom of another condition). Secondary erythromelalgia can result from small fiber peripheral neuropathy of any cause, essential thrombocytosis (erythromelalgia can also develop in the presence of normal platelet counts in patients with myeloproliferative disorder), hypercholesterolemia, mushroom or mercury poisoning, and some autoimmune disorders. Primary erythromelalgia is caused by mutation of the voltage-gated sodium channel α-subunit gene SCN9A.
Hopkins tomorrow episodic burning of hands and feet. They burn often without being red.No swelling is seen either. yrica, cymbalta and amitripitline startedlocal derm also gave me cytotek to try when I was in a great amount of pain. The Cytotek…Continue
Does anyone here with EM use a wheelchair and or collect disability. Lately my EM seems to be getting worse (as I get older). I'm only 31 now so I can't even imagine what it's going to be like in a few years. Just trying to see what I may have ahead…Continue
So spring has arrived with a vengeance. I'm already flared up badly again and house bound in pain. This time my hand has flared up too. Wasn't supposed to see the dermatologist till June because he wanted to see how I was when it was hot out. Last…Continue
I've used an ice pack wrapped in a towel, or just a cool cloth, and while it helps the pain somewhat, the redness does not go away. Does that mean what I have is not EM?Continue
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