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Erythromelalgia (EM) is a rare neurovascular pain disorder that can cause redness and pain in all parts of the body, but most frequently the extremities, such as the hands and feet. It is characterized by intense burning pain, severe redness (erythema), and increased skin temperature that may be episodic or almost continuous in nature. The specific underlying cause of EM remains unknown.
Erythromelalgia may occur either as a primary or secondary disorder (i.e. a disorder in and of itself or a symptom of another condition). Secondary erythromelalgia can result from small fiber peripheral neuropathy of any cause, essential thrombocytosis (erythromelalgia can also develop in the presence of normal platelet counts in patients with myeloproliferative disorder), hypercholesterolemia, mushroom or mercury poisoning, and some autoimmune disorders. Primary erythromelalgia is caused by mutation of the voltage-gated sodium channel α-subunit gene SCN9A.
Hello all, I want to share with you an experience I tried right now ... This will seem horrible to you, but ultimately it is not so! Well, it's been that I like idea of trying a heat desensitization to my feet. For 6 months, I stopped the ice, and I…Continue
Hi, my name is Jenn. I'm 23 years old and was recently diagnosed with EM. This past November, I was given Avelox ( A fluoroquinolone drug ) for a sinus infection. I have suffered severe adverse reactions from this drug. It started out initially with…Continue
I have been having a rough time with my thighs! I have Livedo per derm and i know that isn't supposed to hurt. Problem is my thighs are burning big time.Ouch!! If I get up and move around I am fine.I am becoming really upset by this and fear that…Continue
Hi, I'm new to the group, and I do not have a diagnosis. However, I have been experiencing the symptoms of EM since mid-February. I have been to multiple appointments w/primary care doctor and a rheumatologist twice. When I asked the rheumatologist…Continue
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